Enclomiphene TherapyEnclomiphene Therapy
Stimulates the body's natural testosterone production in men with low levels.
From interest to treatment
A simple, guided process.
- 1
Tell us about yourself
Complete a short medical intake.
- 2
Physician review
A licensed clinician reviews your history and determines if treatment is appropriate.
- 3
Personalized plan
If appropriate, your clinician prescribes your treatment and dosage.
- 4
Delivered to you
Your medication is fulfilled through a licensed pharmacy.
- 5
Ongoing support
We monitor your progress and adjust as needed.
Who Might Consider Estrogen Therapy?
Changes in estrogen levels during perimenopause and menopause can affect everything from daily comfort and intimate health to long-term bone strength. Estrogen therapy offers an effective approach to managing these changes, with treatment options tailored to individual symptoms, health history, and personal needs.
1
Hot Flashes and Night Sweats
Sudden hot flashes and night sweats can interfere with everyday activities, sleep, and overall comfort. Systemic estrogen therapy is one of the most effective treatments for these symptoms, helping reduce their frequency and severity so women can feel more comfortable throughout the day and night.
2
Vaginal Dryness and Intimate Discomfort
Declining estrogen levels can lead to vaginal dryness, irritation, and discomfort during sexual activity. Estrogen therapy helps restore moisture and improve vaginal tissue health, making everyday activities and intimacy more comfortable. Local vaginal estrogen is particularly useful when these symptoms are the primary concern.
3
Recurring Urinary Tract Infections
Hormonal changes during menopause can affect the tissues surrounding the vagina and urinary tract, increasing susceptibility to irritation and recurring infections. Low-dose vaginal estrogen helps maintain healthy local tissues and can reduce the frequency of urinary tract infections in postmenopausal women.
4
Early Menopause and Hormonal Changes
Some women experience menopause earlier than expected, whether naturally or following surgical removal of the ovaries. The sudden or early decline in estrogen can affect physical comfort, hormonal health, and bone strength. Estrogen therapy can help manage these changes while addressing important longer-term health considerations.
5
Bone Health After Menopause
Estrogen plays an important role in maintaining bone strength, and declining levels during menopause can accelerate bone loss. Systemic estrogen therapy helps preserve bone density and reduce fracture risk in appropriately selected women, supporting an important aspect of long-term health.
More Hormonal Health Treatments
Explore our other treatment options that may complement or offer alternatives to Estrogen Therapy.
Progesterone TherapyProgesterone Therapy
Hormone therapy that supports progesterone balance, sleep, and hormonal health.
Testosterone TherapyTestosterone Therapy
Hormone replacement therapy for men with low testosterone levels.
Explore Our Programs
Discover more specialized treatments and services offered at Fountain
Frequently Asked Questions
Everything you need to know about Estrogen Therapy treatment
What is estrogen therapy used for?
Estrogen therapy is commonly used to treat symptoms associated with perimenopause and menopause, including hot flashes, night sweats, vaginal dryness, discomfort during sex, and other symptoms related to declining estrogen levels. The right treatment depends on your symptoms, age, medical history, menopause stage, and individual risk factors. Fountain focuses on improving the symptoms that matter to you rather than trying to reach a universal hormone level.
Can estrogen help with sleep, mood, or brain fog?
It can for some patients, particularly when those symptoms are occurring alongside other changes related to perimenopause or menopause. Hormonal changes can affect sleep, mood, concentration, and mental clarity. At the same time, these symptoms can also be caused by stress, anxiety, depression, thyroid problems, medications, nutritional deficiencies, or sleep disorders. Fountain looks at the full picture rather than assuming every change in mood, sleep, or cognition is caused by estrogen.
How does Fountain decide which type of estrogen therapy to use?
There are several ways estrogen can be prescribed, including patches, gels, oral medications, and vaginal formulations. The best option depends on what symptoms are being treated, your medical history, risk factors, preferences, and whether treatment needs to work throughout the body or primarily in a specific area. Fountain individualizes the route and dose rather than using the same estrogen regimen for every patient.
Do I need progesterone if I take estrogen?
If you are taking systemic estrogen and have not had a hysterectomy, progesterone or another appropriate progestogen is generally used to help protect the uterine lining. If you have had a hysterectomy, your hormone therapy needs may be different. Fountain considers estrogen and progesterone together as part of one coordinated treatment plan based on your symptoms, medical history, and the type of hormone therapy being used.
How long does estrogen therapy take to work?
That depends on the symptom being treated. Hot flashes and night sweats may improve on a different timeline than sleep, vaginal symptoms, mood, or mental clarity. Fountain identifies the specific symptoms treatment is intended to improve and follows those changes over time. Your treatment can then be adjusted based on how well it is working, how you feel, and whether you experience side effects.
Clinically reviewed by
Last reviewed: October 2026
Dr. Doreen Zarfati is Chief Medical Officer at Fountain Health NYC and a double board-certified psychiatrist. Her work spans mental health, longevity, metabolism and sexual health, with a particular interest in how biological and clinical factors can influence psychiatric symptoms and treatment response. At Fountain, Dr. Zarfati provides clinical oversight of Fountain’s care models, reviewing and approving them for clinical use and guiding how they are applied in patient care. Her work in IV ketamine focuses on neuroplasticity, emotional processing and the thoughtful integration of emerging treatments into structured clinical care. Her approach is individualized, collaborative and grounded in measurable response, with treatment evolving as the patient’s clinical picture changes.
Looking for more answers?
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Important Safety Information
Compounded medications are available only to patients who are evaluated by a licensed healthcare provider and receive a prescription when medically appropriate. Prescriptions for compounded medications are filled and dispensed by a licensed compounding pharmacy. Compounded medications are not FDA-approved, and the FDA does not review compounded medications for safety, effectiveness, or quality before they are marketed. Individual results may vary. Product images are for illustrative purposes only and may not reflect the actual medication, packaging, vial, or dosage dispensed.