Satiety
Satiety is the sustained feeling of fullness between meals that delays hunger. Regulated by neuroendocrine signals like GLP-1, PYY, and leptin via the gut-brain axis, it plays a vital role in appetite regulation, metabolic energy balance, and medical weight management.
Differs from satiation (meal ending). Blunted GLP-1 and leptin signaling drive hedonic hunger, requiring receptor-targeted therapy over high-volume foods to restore biological fullness.
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